A spate of injuries might see Ryan Babel up front in the role of a makeshift forward.
Dirk Kuyt and David Ngog have injury concerns. Fernando Torres is already out for the season. Maxi Rodriguez is cup tied and will not be eligible to appear.
The back line is already with Emiliano Insua, Martin Skrtel, and Fabio Aurelio. The Colchoneros are in the front seat, a goal up from the first leg and a draw will suit them fine.
In the future the Reds will get to see Jonjo Shelvey, the 17 year old Charlton Athletic attacking midfielder who is drawing comparisons to Steven Gerrard. Shelvey was signed Tuesday for a fee of £1.7m.